Admission Orders:
General Admission Orders (NEUROLOGY GENERAL ADMISSION MSH IP)
Discuss PLEX versus IVIG with attending
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IVIG:
Check IgA first to avoid anaphylaxis in pts who are IgA depleted, use IgA depleted formulation while awaiting IgA results.
Baseline and Daily CBC, LFT’s, Chem-7, mag, phos
Dose is 0.4g/kg/day X5 days; give with 500cc NS bolus before and after
Risks: aseptic meningitis, rash, renal failure (from sucrose), hyperviscosity stroke, volume overload
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Plasmaphoresis (PLEX):
Contact blood bank attending who oversees PLEX
Shiley placement
Number of sessions determined by attending
Baseline and Daily CBC, LFT’s, Chem-7, PT/PTT, Fibrinogen
Risks: hypotension, sepsis
Consider Tensilon test, LP, EMG, Antibody assays (see below for details)
NIF/VC at least BID
Discuss administration of steroids and mestinon w/attending. Note: mestinon 1mg IV = 30mg PO
Immunization w/inactivated vaccines only